The 2009 Asian study for derivation of common RIs was conducted by the Asia-Pacific Federation of Clinical Biochemistry (APFCB) in collaboration with IFCC and JSCC.
A total of 3500 well-defined healthy subjects were recruited in 64 clinical laboratories in 7 Asian countries.
The assays consisted of 85 commonly-tested analytes, including CBC.
The study not only provided reliable RIs, with consideration of sex and age, but also revealed various biological sources of variation (SV) in many analytes by use of information from a detailed questionnaire: BMI, ABO blood group, menstrual cycle, alcohol, smoking, exercise, etc.
Although major results for 72 analytes and for isozymes for 3 enzymes were published, there is a host of information relevant to laboratory diagnosis which remains unexplored, such as correlations of values between any pair of analytes or commonality of values across the groups of analytes.
This web-site not only provides the documents already published but also offers an interactive graphical data viewer which is useful for the practice and learning of evidence-based laboratory medicine (EBLM).
- Asia-Pacific Federation for Clinical Biochemistry and Laboratory Medicine (APFCB)
Web site: http://www.apfcb.org
- International Federation of Clinical Chemistry and Laboratory Medicine (IFCC)
Web site: http://www.ifcc.org
